Table 1.
Step amplitude, aF | ||
Cav1.3 genotype | Wild type | Ko |
Rest | 43.0 ± 4.0 | 40.4 ± 2.9 |
Depolarized | 38.5 ± 3.6 | 36.0 ± 6.2 |
Rest + Depolarized | 40.2 ± 3.3 | 41.3 ± 3.9 |
Values are presented as mean ± SE and calculated from the median step size per stimulation condition, across five knockout (ko) and seven wild-type patches. Two-sample t test comparisons made between stimulation conditions on the same background, and between genetic backgrounds, gave P values between 0.35 and 0.92. The rest condition consisted of 188 wild-type (wt) and 100 ko events, and the depolarized condition 228 wt and 60 ko events. The number of events per patch ranged from 32 to 99 for wt and from 10 to 50 for ko.