Fig. 4.

Fusion pore conductance (in pS). (A) Estimated conductances (black) calculated using SI Appendix, Eq. S1 and diffusion-corrected pore conductances (red) calculated using SI Appendix, Eq. S3 for trajectory segments in which a continuous water density in the pore lasted for at least 25 ns. Conductance traces are shown for two different cases: long-lived pores (Sim1; Left) and flickering pores (Sim6; Right). (B and C) Distributions of uncorrected (B) and diffusion-corrected (C) conductances for Sim1, Sim2, Sim9, and Sim10. The scale at the top shows corrected conductance values based on the correction factor from atomistic simulation.