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. 2018 Dec 14;37:315. doi: 10.1186/s13046-018-1000-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — X-ray irradiation down-regulates DNMT1, DNMT3b and MeCP2 in lung cancer cells. a Western blot demonstrates the effect of X-ray irradiation on the expression of DNMTs and MeCP2. DNMT1, DNMT3b and MeCP2 were down-regulated significantly in irradiated LK cells compared with non-irradiated cells (P < 0.05), but not obvious change of DNMT3a expression was observed; b The histogram of A; c Decreased expression of DNMT1, DNMT3b and MeCP2 after X-ray irradiation in SPC cells (P < 0.05); d The histogram of C. * P < 0.05