Table 4.
Complete list of the 46 hypomethylated genes.
| Chr | Symbol | ID | Length | Num. CpGs | DMR. p value | DMR. q value | Mean. meth. diff |
|---|---|---|---|---|---|---|---|
| chr8 | Snx1 | NM_053411_I8_introns | 16 | 3 | 0.000178924 | 0.001674221 | 39.23422802 |
| chr10 | Nubp1 | NM_001009619_I9_introns | 51 | 3 | 2.77E-09 | 6.48E-08 | 38.19511889 |
| chr19 | Atp6v0d1 | NM_001011927_I7_introns | 27 | 3 | 8.97E-07 | 1.88E-05 | 37.45568608 |
| chr8 | Bckdhb | NM_019267_I3_introns | 91 | 6 | 4.56E-11 | 1.99E-09 | 36.09637024 |
| chr6 | Prkch | NM_031085_I10_introns | 130 | 4 | 5.03E-06 | 3.02E-05 | 35.65709264 |
| chr13 | Hmcn1 | NM_001271292_I106_introns | 168 | 3 | 4.14E-08 | 4.04E-07 | 35.19645258 |
| chr1 | Zp2 | NM_031150_E10_exon | 79 | 4 | 0.00049086 | 0.001580462 | 33.48819301 |
| chr2 | Ptpn22 | NM_001106460_I13_introns | 70 | 3 | 5.71E-05 | 0.000202829 | 32.53343885 |
| chr2 | Skiv2l2 | NM_001034093_I2_introns | 95 | 4 | 3.00E-08 | 3.49E-07 | 31.5071179 |
| chr1 | Tulp2 | NM_001012168_I1_introns | 110 | 6 | 9.46E-07 | 7.92E-06 | 31.18947695 |
| chr12 | Fry | NM_001170398_I14_introns | 19 | 3 | 2.19E-05 | 0.000288601 | 30.41340002 |
| chr1 | Slco3a1 | NM_177481_I8_introns | 85 | 3 | 0.000528807 | 0.001684136 | 30.13666411 |
| chr1 | Atp10a | NM_001141935_I3_introns | 27 | 6 | 1.03E-06 | 8.14E-06 | 30.06814676 |
| chr1 | Prkg1 | NM_001105731_I15_introns | 70 | 5 | 0.000356284 | 0.001186265 | 28.94112061 |
| chr4 | Grm7 | NM_031040_I7_introns | 192 | 3 | 0.000245364 | 0.001003763 | 28.53745911 |
| chr10 | Carhsp1 | NM_152790_I2_introns | 102 | 5 | 2.26E-05 | 0.000211468 | 28.25784027 |
| chr2 | Noct | NM_138526_I1_introns | 17 | 3 | 0.000373085 | 0.000889665 | 28.10593157 |
| chr15 | Gpc5 | NM_001107285_I2_introns | 205 | 4 | 2.72E-09 | 2.44E-08 | 27.84298084 |
| chr16 | Nrg1 | NM_001271130_I1_introns | 272 | 4 | 0.000226123 | 0.000621838 | 27.46776641 |
| chr7 | Dmc1 | NM_001130567_I6_introns | 134 | 3 | 0.000623225 | 0.001671375 | 27.18046865 |
| chr8 | Tex264 | NM_001007665_I3_introns | 13 | 4 | 4.67E-12 | 3.06E-10 | 26.94493645 |
| chr1 | Oprm1 | NR_027877_I3_introns | 167 | 4 | 5.98E-05 | 0.000236705 | 26.39509712 |
| chr1 | Ntrk3 | NM_001270655_I14_introns | 19 | 4 | 0.000915163 | 0.00273615 | 26.34513213 |
| chr6 | Psma3l | NM_001004094_I5_introns | 128 | 3 | 1.84E-06 | 1.57E-05 | 26.13483738 |
| chr6 | Psma3 | NM_017280_I5_introns | 128 | 3 | 1.84E-06 | 1.57E-05 | 26.13483738 |
| chr7 | Cpq | NM_031640_I8_introns | 174 | 5 | 0.000464492 | 0.001305002 | 25.03471249 |
| chr1 | Tpd52l1 | NM_001044295_I1_introns | 43 | 4 | 2.22E-06 | 1.41E-05 | 24.99670494 |
| chr1 | RGD1307603 | NM_001134508_E3_exon | 35 | 6 | 6.18E-05 | 0.000241568 | 24.98945466 |
| chr19 | Gfod2 | NM_001107421_I2_introns | 100 | 9 | 4.56E-06 | 6.38E-05 | 24.49436882 |
| chr10 | Cyth1 | NM_053910_E12_exon | 56 | 6 | 2.55E-05 | 0.000217367 | 24.45542274 |
| chr13 | Gpatch2 | NM_001011909_I1_introns | 258 | 3 | 9.48E-05 | 0.000369638 | 23.92339964 |
| chr9 | Myo1b | NM_053986_I3_introns | 136 | 6 | 8.64E-05 | 0.000351935 | 23.4475614 |
| chr18 | Ldlrad4 | NM_001271365_I5_introns | 494 | 14 | 5.50E-07 | 5.39E-06 | 23.43565697 |
| chr6 | Frmd6 | NM_001271054_I1_introns | 304 | 4 | 0.000701646 | 0.001871057 | 23.28083922 |
| chr1 | Plpp4 | NM_001191631_I5_introns | 86 | 3 | 1.05E-05 | 5.31E-05 | 23.22492261 |
| chr1 | Gpr139 | NM_001024241_I1_introns | 38 | 3 | 0.00021821 | 0.000752181 | 22.95290692 |
| chr10 | Ccdc40 | NM_001134688_I1_introns | 38 | 4 | 4.16E-05 | 0.000338144 | 22.84818656 |
| chr13 | Cntnap5b | NM_001047873_I1_introns | 329 | 3 | 1.10E-05 | 6.16E-05 | 22.56555396 |
| chr19 | Zfp612 | NM_001107428_I3_introns | 169 | 5 | 0.000905479 | 0.004444048 | 22.51841655 |
| chr8 | Dpp8 | NM_001108159_I13_introns | 120 | 13 | 0.000326038 | 0.002512407 | 22.4358468 |
| chr9 | Sphkap | NM_001127492_I13_introns | 199 | 4 | 0.000143173 | 0.000508033 | 21.12261507 |
| chr1 | Ipcef1 | NM_001170799_I1_introns | 88 | 4 | 0.000961996 | 0.002847121 | 20.82969003 |
| chr5 | Slco5a1 | NM_001107898_I1_introns | 62 | 3 | 8.67E-05 | 0.000473983 | 20.47392161 |
| chr4 | Prickle2 | NM_001107876_I1_introns | 181 | 7 | 0.000537784 | 0.001861562 | 20.45460701 |
| chr1 | Hddc2 | NM_001108460_I2_introns | 61 | 4 | 2.61E-05 | 0.000112648 | 20.32430339 |
| chr9 | Kcnh8 | NM_145095_I9_introns | 302 | 5 | 3.28E-05 | 0.000150472 | 20.01509207 |