Table 6.
KEGG pathway analysis of aberrantly methylated-differentially expressed genes in spinal cord injury.
| Pathway name | Gene num | P-value | Genes |
|---|---|---|---|
| Hypermethylation | |||
| Calcium signaling pathway | 7 | 0.001367652 | Htr7, Gna14, Adra1a, Cysltr2, Itpr3, Ppp3cc, Slc8a1 |
| Endocytosis pathway | 6 | 0.041783996 | Acap1, Ehd4, Rab11fip4, Sh3kbp1, Smurf1, Dnm3 |
| T cell receptor signaling pathway | 4 | 0.020396716 | Csf2, Ctla4, Ppp3cc, Vav2 |
| Axon guidance | 4 | 0.053653812 | Dpysl2, Plxna2, Ppp3cc, Robo2 |
| Dopaminergic synapse | 4 | 0.054679627 | Arntl, Itpr3, Ppp2r2a, Ppp3cc |
| Taste transduction | 3 | 0.053663995 | Asic2, Itpr3, Trpm5 |
| Hypomethylation | |||
| Endocytosis pathway | 6 | 0.041783996 | Arfgef1, Flt1, Cyth1, Dnm3, Snx1, Spg21 |
| Hippo signaling pathway | 4 | 0.082043834 | Frmd6, Bmp5, Ctnna2, Dlg2 |