Neuroprotective effect of intranasal CGRP treatment. (A) ELISA detected the protein level of CGRP. (B) TTC staining showed the infarct volume of the indicated groups. (C) H & E staining showed the pathological injury of the indicated groups. * P<0.05, compared to the sham group; #
P<0.05, ##
P<0.01, compared to the MCAO group. (D) H & E staining showed the pathological injury of the indicated groups. * P<0.05, compared to the sham group; #
P<0.05, ##
P<0.01, compared to the MCAO group. CGRP – calcitonin gene-related peptide; ELISA – enzyme-linked immunosorbent assay; TTC – 2, 3, 5-triphenyltetrazolium chloride; H & E – hematoxylin and eosin; MCAO – middle cerebral artery occlusion.