Table 5b.
Clinical Characteristics of Children with ASD by Concomitant Condition1
| Co-occuring Disorder Group |
CGI-Severity | ASD Score | CGI-Improvement (N = 478) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Moderate (N = 199) |
Marked (N = 327) |
Severe (N = 129) |
p- value3 |
≤ 20 (N = 333) |
> 20 (N = 321) |
p-value | Non Response (N = 189) |
Positive Responder (N = 289) |
p-value | |
| ADHD | 161 (80.9%) | 262 (80.1%) | 109 (83.9%) | 0.573 | 255 (76.6%) | 277 (86.3%) | 0.001* | 157 (83.1%) | 232 (80.3%) | 0.443 |
| ODD | 84 (42.2%) | 144 (44.0%) | 69 (53.5%) | 0.060 | 146 (43.8%) | 153 (47.7%) | 0.327 | 71 (37.6%) | 148 (51.2%) | 0.003* |
| CD | 20 (10.1%) | 33 (10.1%) | 24 (18.6%) | 0.035* | 30 (9.0%) | 47 (14.7%) | 0.025* | 24 (12.8%) | 31 (10.7%) | 0.496 |
| Any Anxiety Disorder | 80 (40.2%) | 140 (42.8%) | 55 (42.6%) | 0.619 | 124 (37.2%) | 150 (46.7%) | 0.014* | 80 (42.3%) | 120 (41.5%) | 0.861 |
| Any Mood Disorder | 20 (10.1%) | 24 (7.3%) | 5 (3.9%) | 0.037* | 19 (5.7%) | 30 (9.4%) | 0.077 | 9 (4.8%) | 28 (9.7%) | 0.049 |
| Internalizing Disorder | 84 (42.4%) | 149 (45.6%) | 57 (44.2%) | 0.654 | 132 (39.6%) | 157 (48.9%) | 0.017* | 85 (45.0%) | 126 (43.6%) | 0.767 |
| Externalizing Disorder | 173 (86.9%) | 277 (84.7%) | 116 (89.9%) | 0.570 | 276 (82.9%) | 290 (90.3%) | 0.005* | 165 (87.3%) | 252 (87.2%) | 0.973 |
| At least 2 additional dx* | 127 (63.8%) | 217 (66.4%) | 89 (68.5%) | 0.375 | 206 (61.9%) | 228 (71.0%) | 0.013* | 126 (66.7%) | 198 (68.5%) | 0.673 |
1
Groups are not mutually exclusive
2
Percents are percent of the column with the indicated diagnosis
3
Test for trend; Treating CGI as an ordinal outcome