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. Author manuscript; available in PMC: 2019 Nov 1.
Published in final edited form as: Wound Repair Regen. 2018 Oct 24;26(6):403–412. doi: 10.1111/wrr.12674

Figure 3. Topical nAChR activation normalizes AMP activity and hydrophobicity in MRSA-infected mouse wounds in diabetic mice.

Figure 3.

Wounds from vehicle treated (A-B) or nicotine treated (C-D) control Leprdb/+ and spontaneous diabetic Leprdb/db mice were infected with MRSA bacteria and excised at day 1 post-wounding/infection and subjected to HPLC fractionation and radial diffusion assay. Bacterial growth inhibition diameters were measured using ImageJ software. Data were statistically analyzed by ANOVA and Sidak’s post-test (*, p<0.05 vs. control mouse fraction). N=4–5 samples/group.