Figure 7. Lack of a Therapeutic Effect of MSC MVs on Lung Compliance or Oxygenation following Severe Escherichia coli Pneumonia in Ex Vivo Perfused Human Lung.
Administration of MSC MVs or Poly (I:C) pretreated MSC MVs had no significant effect on tracheal pressure (A), lung compliance (B) or oxygenation (C) over 6 h. Data is presented as median Tracheal pressure or Lung Compliance or PaO2 with IQR as bars. P = 0.56 – 0.98 for each time point by Kruskal Wallis tests (A). P = 0.56 – 0.98 for each time point by Kruskal Wallis tests (B). P = 0.10 – 0.92 for each time point by Kruskal Wallis tests (C).