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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: J Allergy Clin Immunol. 2018 Jun 18;143(2):726–735. doi: 10.1016/j.jaci.2018.04.027

FIG 5.

FIG 5.

Recombination activity of compound heterozygous RAG2 variants. A, Analysis of the recombination activity supported by bicistronic vectors simultaneously expressing 2 RAG2 variants and comparison with recombination activity of single variants. Experiments were done in triplicates. B, Pearson correlation analysis between recombination activity supported by bicistronic vectors versus number of unique sequences. C, Graphic representation of Igh repertoire diversity. D, Quantitative measurement of diversity and unevenness of the Igh repertoire.