Table 5.
Correlation between metabolite levels and expected time to onset of AD
| Spearman ρ, years until expected diagnosis | p | ||
|---|---|---|---|
| LpAC | Cho | −0.29 | 0.344 |
| Cr | −0.37 | 0.212 | |
| Gx | 0.36 | 0.229 | |
| mI | −0.88 | 0.00007* | |
| NAA | −0.50 | 0.079 | |
| RpAC | Cho | −0.17 | 0.578 |
| Cr | −0.48 | 0.097 | |
| Gx | −0.45 | 0.123 | |
| mI | −0.45 | 0.123 | |
| NAA | −0.01 | 0.969 | |
| mPCG | Cho | −0.76 | 0.003 |
| Cr | −0.68 | 0.010 | |
| Gx | −0.26 | 0.388 | |
| mI | −0.76 | 0.003 | |
| NAA | −0.41 | 0.160 | |
| mPC | Cho | −0.52 | 0.072 |
| Cr | −0.46 | 0.117 | |
| Gx | −0.66 | 0.015 | |
| mI | −0.84 | 0.00034* | |
| NAA | 0.04 | 0.890 |
LpAC: left pregenual anterior cingulate gyrus; RpAC: right pregenual anterior cingulate gyrus; mPCG: midline posterior cingulate gyrus; mPC: midline precuneus
*
significant after Holm-Bonferroni correction for multiple comparisons