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. 2018 Dec;7(6):429–439. doi: 10.21037/hbsn.2018.10.07

Table 1. Correlation of HOTTIP expression with clinicopathological features of human HCC.

Variables Tumor HOTTIP expression Pa
Low High
Age 0.453
   ≤50 years 40 41
   >50 years 41 33
Gender 0.063
   Male 77 64
   Female 4 10
PVTT 0.357
   Absent 55 45
   Present 26 29
Preoperative AFP level 0.892
   ≤400 ng/mL 37 33
   >400 ng/mL 44 41
Histopathologic grading 0.142
   Well + moderately 50 37
   Poorly 31 37
Tumor size 0.105
   ≤5 cm 52 38
   >5 cm 39 36
Tumor number 0.262
   Single 39 29
   Multiple 42 45

HCC patients receiving LT were segregated into HOTTIP-high/low expression groups (calculation of cut-off was performed by receiver operating characteristics analysis). a, statistical analyses were performed with the Chi-square test. HCC, hepatocellular carcinoma; AFP, alpha-fetoprotein; PVTT, portal vein tumor thrombi.