Table 1. Correlation of HOTTIP expression with clinicopathological features of human HCC.
Variables | Tumor HOTTIP expression | Pa | |
---|---|---|---|
Low | High | ||
Age | 0.453 | ||
≤50 years | 40 | 41 | |
>50 years | 41 | 33 | |
Gender | 0.063 | ||
Male | 77 | 64 | |
Female | 4 | 10 | |
PVTT | 0.357 | ||
Absent | 55 | 45 | |
Present | 26 | 29 | |
Preoperative AFP level | 0.892 | ||
≤400 ng/mL | 37 | 33 | |
>400 ng/mL | 44 | 41 | |
Histopathologic grading | 0.142 | ||
Well + moderately | 50 | 37 | |
Poorly | 31 | 37 | |
Tumor size | 0.105 | ||
≤5 cm | 52 | 38 | |
>5 cm | 39 | 36 | |
Tumor number | 0.262 | ||
Single | 39 | 29 | |
Multiple | 42 | 45 |
HCC patients receiving LT were segregated into HOTTIP-high/low expression groups (calculation of cut-off was performed by receiver operating characteristics analysis). a, statistical analyses were performed with the Chi-square test. HCC, hepatocellular carcinoma; AFP, alpha-fetoprotein; PVTT, portal vein tumor thrombi.