Table 3. HOTTIP expression in HCC is an independent predictive factor for recurrence and overall survival in patients following LT.
| Variables | Cumulative recurrence | Overall survival | |||
|---|---|---|---|---|---|
| HR (95% CI) | Pa | HR (95% CI) | Pa | ||
| Milan criteria (beyond vs. meeting) | 2.600 (1.183–5.716) | 0.016 | 2.425 (1.098–5.357) | 0.027 | |
| PPTV (present vs. absent) | 1.793 (1.123–2.863) | 0.014 | 1.648 (1.019–2.665) | 0.040 | |
| Tumor size (>5 vs. ≤5 cm) | 1.892 (1.140–3.139) | 0.011 | 2.094 (1.245–3. 522) | 0.004 | |
| HOTTIP expression (high vs. low) | 1.805 (1.175–2.773) | 0.006 | 1.715 (1.106–2.659) | 0.015 | |
a, Cox proportional hazards regression. HCC, hepatocellular carcinoma; LT, liver transplantation.