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. 2018 Nov;80(4):571–582. doi: 10.18999/nagjms.80.4.571

Table 2.

Predictive value for 30-day survival of blood test data

Blood test data AUC Optimal cut-off value Univariate analysis Multivariate analysis
Number of
patients
30-day
survival
(%)
p Odds ratio
for 30-day
mortality
95%CI p
C-reactive protein 0.6752 5.4 mg/dL ≧5.4 385 29.4% <0.0001 1.86 1.30 – 2.67 0.0007
<5.4 376 55.5% 1
Albumin 0.6275 2.8 g/dL ≧2.8 294 56.0% <0.0001 1 0.0006
<2.8 467 33.7% 1.9 1.31 – 2.76
Total bilirubin 0.5909 1.3 mg/dL ≧1.3 151 23.8% <0.0001 1.55 0.93 – 2.62 0.0953
<1.3 610 46.8% 1
Aspartate
aminotransferase (AST)
0.5783 47 IU/L ≧47 218 47.3% <0.0001
<47 243 31.2%
Alanine aminotransferase (ALT) 0.6141 19 IU/L ≧19 401 33.5% <0.0001 1.44 0.99 – 2.29 0.0511
<19 360 54.0% 1
Blood urea nitrogen (BUN) 0.6782 21 mg/dL ≧21 354 27.8% <0.0001 1.98 1.33 – 2.95 0.0007
<21 407 54.8% 1
Creatinine 0.5481 1.09 mg/dL ≧1.09 168 25.8% <0.0001 1.80 0.86 – 3.79 0.1172
<1.09 593 46.9% 1
Estimated glomerular filtration rate (eGFR) 0.5577 45 ml/min/ 1.73 m2 ≧45 596 46.6% <0.0001 1 0.5568
<45 165 27.3% 1.25 0.60 – 2.64
White blood cell count 0.6589 8.600 × 103/μL ≧8.600 417 30.2% <0.0001 1.47 1.00 – 2.15 0.0495
<8.600 344 57.0% 1
Basophil 0.5940 0.1 % ≧0.1 605 46.6% <0.0001 1 0.4266
<0.1 156 25.4% 1.22 0.75 – 2.00
Eosinophil 0.6524 0.8 % ≧0.8 304 59.0% <0.0001 1 0.0349
<0.8 457 32.7% 1.50 1.03 – 2.18
Neutrophil 0.6551 83.7 % ≧83.7 300 25.9% <0.0001 1.02 0.59 – 1.78 0.9329
<83.7 461 53.0% 1
Lymphocyte count 0.4352 2.218 × 103/μL ≧2.218 × 103 60 26.7% 0.0019 1.84 0.92 – 3.81 0.0847
<2.218 × 103 701 43.6% 1
Neutrophil-to-lymphocyte ratio (N/L) 0.6684 11.1 ≧11.1 257 22.5% <0.0001 2.23 1.29 – 3.91 0.0043
<11.1 504 54.3% 1
Red blood cell count 0.5163 4.17 × 106/μL ≧4.17 × 106 96 32.9% 0.0309
≧4.17 × 106 665 43.6%
Hemoglobin 0.5016 13.2 g/dL ≧13.2 51 30.4% 0.0101 2.54 1.34 –4.96 0.0041
< 13.2 687 43.5%
Hematocrit 0.5011 34.70% ≧34.7 186 37.4% 0.0749
<34.7 575 43.8%
Mean corpuscular volume (MCV) 0.5433 93.7 fL ≧93.7 295 49.9% <0.0001 1 0.0001
<93.7 466 37.5% 2.07 1.43 – 3.02
Red cell distribution width (RDW) 0.5871 16 ≧16 474 35.4% 0.0027 1.71 1.19 – 2.46 0.0034
<16 287 53.4% 1
Platelet count 0.5473 159 × 103/μL ≧159 × 103 605 45.9% <0.0001 1 0.0007
<159 × 103 156 28.2% 2.19 1.39 – 3.50

Bold values indicate statistical significance (p<0.05).