Table 1.

Potential factors contributing to TMEV-induced organ-specific pathology.

	CNS	Heart
Infection of major cell type in vitro	+ (Neuro-2a)	+ (HL-1)
Innate immune response by major cell type in vitro	–	+
Infection in vivo	+	+
Lymphatics	Lymphatic molecule downregulation?	Cytokine-induced functional suppression