Fig. 5.

The effect on compensatory neuromodulators of a muscarinic receptor antagonists dialyzed into the ventral respiratory column is state independent as indicated by the finding that the mock cerebral spinal fluid (mCSF) effluent concentration of serotonin (5-HT; A), glycine (B), γ-aminobutyric acid (GABA; C) did not differ (P > 0.05) between awake and isoflurane anesthesia studies. The 1st and 2nd bars for each hour represent awake and anesthetized states, respectively. F and P values are from two-way repeated measures ANOVA.