Fig. 6.

Release of compensatory neuromodulators in response to a muscarinic receptor antagonist is locally mediated and not reflex as indicated by increases in serotonin (5-HT; A) and glycine (B) at the site of 50 mM atropine (ATR) dialysis but not at the contralateral site. Data are from an individual goat studied on 2 different dates with mock cerebral spinal fluid (mCSF) dialyzed for 3 h at one site, and on alternate days, 50 mM atropine were dialyzed at the contralateral site during hour 2 of dialysis.