Fig. 16.

Increased activation of µ-opioid inhibitory receptors by unilateral dialysis of 100 µM [d-Ala2,N-MePhe4,Gly-ol]-enkephalin (DAMGO) into the hypoglossal motor nuclei decreased activation of the genioglossal muscle (closed circles), but did not alter activation of the diaphragm (open circles). F and P values are from two-way ANOVA comparing dialysis of DAMGO during hour 3 and dialysis of mCSF all 3 h. *P < 0.001 comparisons to the pre DAMGO dialysis period by post hoc analysis (Holm-Sidak).