Fig. 1.

Mean arterial pressure (MAP) and heart rate (HR) in sham-operated (SHAM) or ovariectomized (OVX) salt-resistant (SR) and salt-sensitive (SS) rats from 4 to 7 mo of age. After being weaned, all rats were maintained on a low-sodium diet (<0.13% NaCl). Ovariectomies or sham surgeries were conducted at 3 mo. Shown is the MAP (A) and HR (B) from 4 to 7 mo of age measured by radio telemetry. The data in SR-SHAM (n = 3), SR-OVX (n = 2), SS-SHAM (n = 3), and SS-OVX (n = 4) are expressed as means ± SE; *P < 0.05 vs. SHAM, same strain or #P < 0.0001 vs. SR, same gonadal status, by Tukey’s multiple comparison in two-way ANOVA; SS/JrHsd/Env, salt-sensitive rats developed by John Rapp, distributed by Harlan, and purchased from Envigo; SR/JrHsd/Env, salt-resistant rats developed by John Rapp, distributed by Harlan, and purchased from Envigo.