Table 1.
Measurement | SR-SHAM (n = 7) | SR-OVX (n = 6) | SS-SHAM (n = 7) | SS-OVX (n = 5) |
---|---|---|---|---|
Age, mo | 10 | 10 | 10 | 10 |
Initial body weight, g | 149 ± 5 | 136 ± 5 | 161 ± 5 | 158 ± 3* |
Final body weight, g | 275 ± 5 | 351 ± 19# | 322 ± 8* | 337 ± 8 |
Left kidney, g | 0.8 ± 0.02 | 0.8 ± 0.01 | 1 ± 0.01 | 1 ± 0.07# |
Left kidney, g normalized to 100 g body wt | 0.3 ± 0.007 | 0.31 ± 0.007# | 0.3 ± 0.005 | 0.3 ± 0.03 |
Right kidney, g | 0.8 ± 0.03 | 0.9 ± 0.01 | 1 ± 0.01 | 1 ± 0.07 |
Right kidney, g normalized to 100 g body wt | 0.3 ± 0.008 | 0.3 ± 0.01# | 0.3 ± 0.007 | 0.3 ± 0.06 |
Heart, g | 0.8 ± 0.02 | 0.9 ± 0.03 | 1 ± 0.03 | 1 ± 0.06 |
Heart normalized to 100 g body wt, g | 0.3 ± 0.008 | 0.3 ± 0.01# | 0.3 ± 0.007 | 0.3 ± 0.03 |
Uterus, g | 0.6 ± 0.02 | 0.2 ± 0.07# | 0.6 ± 0.04 | 0.4 ± 0.03# |
Uterus normalized to 100 g body wt, g | 0.2 ± 0.01 | 0.06 ± 0.03# | 0.2 ± 0.02 | 0.1 ± 0.008# |
Data are expressed as means ± SE; n, number of rats. All rats were maintained on a low-sodium diet (<0.13% NaCl) since weaning. Ovariectomies (OVX) or sham surgeries (SHAM) were conducted at 6 wk of age. Shown are body and tissue weights of 10-mo-old salt-sensitive (SS) and salt-resistant (SR) rats.
P < 0.05 vs. SR, same gonadal status;
P < 0.05 vs. SHAM, same strain; two-way ANOVA and Sidak’s post hoc analysis.