Table 2.

Body weight and tissue weight in SHAM and OVX 1- and 8-mo-old SS and SR rats

Measurement	SS (n = 13)	SR-SHAM (n = 3)	SR-OVX (n = 2)	SS-SHAM (n = 3)	SS-OVX (n = 4)
Age, mo	1	8	8	8	8
Initial body weight, g		229 ± 3	221 ± 4	261 ± 6*	261 ± 4*
Final body weight, g	125 ± 4	275 ± 7	308 ± 9	315 ± 13*	361 ± 7*#
Left kidney, g	0.5 ± 0.02	0.9 ± 0.04	0.8 ± 0.04	1 ± 0.05	1 ± 0.06*
Left kidney normalized to 100 g body wt, g	0.4 ± 0.01	0.3 ± 0.01	0.3 ± 0.01#	0.3 ± 0.01	0.3 ± 0.02
Right kidney, g	0.6 ± 0.01	0.8 ± 0.02	0.8 ± 0.03	1 ± 0.04*	1 ± 0.07
Right kidney normalized to 100 g body wt, g	0.5 ± 0.01	0.3 ± 0.002	0.3 ± 0.008	0.3 ± 0.02	0.3 ± 0.02
Heart, g	0.5 ± 0.01	0.8 ± 0.03	0.8 ± 0.02	1 ± 0.03*	2 ± 0.05*
Heart normalized to 100 g body wt, g	0.5 ± 0.01	0.3 ± 0.005	0.3 ± 0.004	0.5 ± 0.009*	0.4 ± 0.01*
Uterus, g		0.5 ± 0.09	0.2 ± 0.02#	0.6 ± 0.08	0.3 ± 0.07#
Uterus normalized to 100 g body wt, g		0.2 ± 0.03	0.06 ± 0.007#	0.2 ± 0.03	0.08 ± 0.02#

Data are expressed as means ± SE; n, number of rats. All rats were maintained on a low-sodium diet (<0.13% NaCl) since weaning. Ovariectomies (OVX) or sham surgeries (SHAM) were conducted at 3 mo of age. Shown are body and tissue weights of 1-mo-old and 8-mo-old salt-sensitive (SS) and 8-mo-old salt-resistant (SR) rats.

^*P < 0.05 vs. SR, same gonadal status;

^#P < 0.05 vs. SHAM, same strain; two-way ANOVA and Sidak’s post hoc analysis.