Table 2.
Negatively correlating gene transcripts. Gene transcripts showing a negative correlation with DEP relative abundance in normoxic and hyperoxic lungs
| Gene | Correlation Coefficient | P value |
|---|---|---|
| p-AMPKb1 (S108) differentially expressed | ||
| Hyperoxia | ||
| HTRA1 | −0.999 | 0.001 |
| AGT | −0.996 | 0.004 |
| HIST2H2AC | −0.994 | 0.006 |
| HOXB5 | −0.990 | 0.010 |
| CD82 | −0.989 | 0.011 |
| DNAJC15 | −0.985 | 0.015 |
| EIF5 | −0.979 | 0.021 |
| HIST1H2AO | −0.975 | 0.025 |
| HDC | −0.968 | 0.032 |
| D8ERTD82E | −0.964 | 0.036 |
| ADCY8 | −0.951 | 0.049 |
| Normoxia | ||
| MEGF10 | −0.996 | 0.004 |
| ATP6AP2 | −0.991 | 0.009 |
| ENPP5 | −0.985 | 0.015 |
| GSTA3 | −0.974 | 0.026 |
| GCNT2 | −0.963 | 0.037 |
| GUCY1B3 | −0.961 | 0.039 |
| PDGFRb (28E1) differentially expressed | ||
| Hyperoxia | ||
| BC034076 | −0.983 | 0.017 |
| KCNK3 | −0.975 | 0.025 |
| DNAIC1 | −0.974 | 0.026 |
| Normoxia | ||
| MEST | −0.986 | 0.014 |
| DLK1 | −0.983 | 0.017 |
| EXOC4 | −0.968 | 0.032 |
| EIF5 | −0.965 | 0.035 |
| LAMP2 | −0.964 | 0.036 |
| HOXB5 | −0.955 | 0.045 |
| Slug (C19G7) differentially expressed | ||
| Hyperoxia | ||
| ADAM28 | −0.996 | 0.004 |
| MEGF10 | −0.987 | 0.013 |
| CCDC85B | −0.985 | 0.015 |
| CLIC6 | −0.984 | 0.016 |
| LOC100046120 | −0.979 | 0.021 |
| CKMT1 | −0.970 | 0.030 |
| Normoxia | ||
| LMNA | −1.000 | 0.000 |
| ANGPT2 | −0.999 | 0.001 |
| ENPP5 | −0.979 | 0.021 |
| GUCY1B3 | −0.964 | 0.036 |
| HSPB8 | −0.961 | 0.039 |
| AHNAK | −0.961 | 0.039 |
| IGFBP2 | −0.956 | 0.044 |
See main text for relevant definitions.