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. 2018 Aug 9;315(5):L752–L764. doi: 10.1152/ajplung.00208.2018

Fig. 5.

Fig. 5.

Induced sputum (IS) macrophages (MAC) rely on glycolysis. A: glycolytic stress test with the sequential addition of glucose and oligomycin (Oligo) provides measurements of three glycolytic parameters using the extracellular acidification rate (ECAR). B: ECAR was measured in MAC sampled from the upper airways (IS) or bronchoalveolar region [bronchoalveolar lavage (BAL)] of normal volunteers in response to the glycolytic stress test. Representative ECAR plots are shown for each sample type. C–E: individual parameters derived from the data produced by the glycolytic stress test described in A for IS and BAL MAC. ***P < 0.001 and ****P < 0.0001 for comparison of group means. Shown are means ± SD, IS (n = 11) and BAL (n = 13). Rot./Ant. A, rotenone/antimycin A.