Table 7.
Canonical pathways from Ingenuity Pathway Analysis with a significant enrichment of genes with association P < 0.01 for survival without BPD
| Canonical Pathway | No. of Genes (%) | Genes in Pathway with P < 0.01 | P Value |
|---|---|---|---|
| Agranulocyte adhesion and diapedesis | 9/181 (4.8) | CCL3, CCL4, CCL17, CCL18, CCL22, CLDN17, CX3CL1, MYL9, RDX | 3.06 × 10−5 |
| Granulocyte adhesion and diapedesis | 8/181 (4.4) | CCL3, CCL4, CCL17, CCL18, CCL22, CLDN17, CX3CL1, RDX | 1.22 × 10−4 |
Statistical significance was determined using a Bonferroni adjustment for 209 canonical pathways tested (α = 2.39 × 10−4). BPD, bronchopulmonary dysplasia.