Table 7.
Integrative analysis between DNA methylation and DE-genes.
| Gene ID | Symbol | Gene expression fold change | Methylation fold change |
|---|---|---|---|
| Positively correlated | |||
| NM_016687 | Sfrp4 | -4.59 | -1.07348337 |
| NM_026257 | Ubxn11 | -3.457 | -1.03471761 |
| NM_175199 | Hspa 12a | -3.145 | -1.46219747 |
| NM_013460 | Adrald | -2.851 | -1.38134037 |
| NM_008714 | Notch 1 | -1.568 | -1.53733423 |
| NM_009359 | Tex9 | -1.225 | -1.12112261 |
| NM_010806 | Afdn | -0.776 | -1.51548783 |
| NM_146155 | Ahdd | -0.726 | -1.03777499 |
| NM_029348 | Zbtb4 | -0.64 | -2.07882427 |
| NM_178878 | Hadha | -0.555 | -1.40843417 |
| NM_173741 | Wdr24 | -0.537 | -1.08835819 |
| NM_133740 | Prmt3 | 0.522 | 1.27886894 |
| NM_001008421 | Nol10 | 0.62 | 1.34590795 |
| NM_008084 | Gapdh | 0.836 | 1.51507841 |
| NM_007400 | Adam12 | 3.106 | 1.18884493 |
| Negatively correlated | |||
| NM_008909 | Ppl | -3.537 | 1.02814109 |
| NM_009931 | Col4a1 | -1.111 | 1.18884493 |
| NM_028200 | Vps9d1 | -0.89 | 1.32210035 |
| NM_033563 | Klf7 | -0.633 | 1.48896494 |
| NM_054044 | Adgra2 | -0.392 | 1.62011388 |
| NM_009211 | Smarcd | 0.608 | -1.04303283 |
| NM_172585 | Larp4b | 0.608 | -1.47577455 |
| NM_001081321 | Pds5a | 0.644 | -1.03048504 |
| NM_024452 | Luzp1 | 0.747 | -1.27570871 |
| NM_178661 | Creb3l2 | 0.837 | -1.08859245 |
| NM_024472 | Cptp | 0.862 | -1.27774791 |
| NM_177644 | Rasal2 | 1.228 | -1.14013994 |
| NM_144515 | Zfp52 | 1.257 | -1.33247327 |
| NM_028778 | Nuak2 | 1.581 | -1.20811393 |
| NM_153287 | Csrnp1 | 1.748 | -1.30599888 |
| NM_026473 | Tubb6 | 1.983 | -1.15399286 |
| ∗NM_008120 | Gja4 | 3.703 | -1.38683764 |
The DE-gene with methylation are listed to show the gene expression is related to methylation, including the gene expression with both positive and negative correlation to DNA methylation. A scatter plot graph shows these genes based on gene expression level and methylation status fold (Figure 4).