Table 2.
Demographic, clinical, and echocardiographic features.
| Control (n = 25) | SSc (n = 25) | P value | |
|---|---|---|---|
| Female sex (%) | 23 (92%) | 23 (92%) | 1.0 |
| BSA (m2) | 1.7 ± 0.2 | 1.6 ± 0.1 | 0.67 |
| Age (years) | 65 ± 9 | 66 ± 9 | 0.60 |
| WHO FC | |||
| I | 20 (80%) | 17 (68%) | |
| II | 5 (20%) | 8 (32%) | |
| III | 0 (0%) | 0 (0%) | |
| IV | 0 (0%) | 0 (0%) | |
| Systolic BP (mmHg) | 126 ± 14 | 130 ± 15 | 0.39 |
| Diastolic BP (mmHg) | 69 ± 6 | 69 ± 7 | 0.92 |
| Heart rate (bpm) | 77 ± 9 | 79 ± 10 | 0.42 |
| H2FPEF score | 1.3 ± 0.8 | 1.2 ± 0.8 | 0.48 |
| Echocardiography | |||
| LAVI (mL/m2) | 23 ± 7 | 25 ± 6 | 0.11 |
| LVEDd (mm) | 45 ± 5 | 47 ± 6 | 0.28 |
| LVESd (mm) | 28 ± 5 | 29 ± 4 | 0.15 |
| IVS (mm) | 10 ± 3 | 10 ± 4 | 0.79 |
| PW (mm) | 9 ± 4 | 8 ± 4 | 0.26 |
| LVEF (%) | 60 ± 5 | 62 ± 4 | 0.18 |
| TAPSE (mm) | 24 ± 5 | 22 ± 4 | 0.29 |
| IVC (mm) | 14 ± 6 | 13 ± 8 | 0.32 |
| E/A | 1.4 ± 0.5 | 1.2 ± 0.4 | 0.15 |
| E/e′ | 5.8 ± 2.0 | 7.2 ± 2.7 | 0.02 |
Continuous variables are expressed as mean ± standard deviation.
A, A wave; BP, blood pressure; bpm: beats per minute; BSA, body surface area; E, E wave; e’, E wave at mitral annulus; H2FPEF, clinical and echocardiographic score for calculating the probability of heart failure with preserved ejection fraction; ICV, inferior cava vein; LAVI, left atrium volume index; IVS, interventricular septum; LVEDd, left ventricular end-diastolic diameter; LVEF, left ventricular ejection fraction; LVESd, left ventricular end-systolic diameter; PW, posterior wall; TAPSE, tricuspid annulus plane systolic excursion; WHO FC, World Health Organization functional class.