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Effects of fipronil on GABA-evoked currents. Top panel, representative current traces evoked by GABA (EC30–50) in the presence of increasing concentrations of fipronil in X. laevis oocytes that express VdesRDL1, VdesRDL2, VdesRDL3, or VdesGRD/LCCH3. The duration of GABA perfusion was adjusted for each oocyte to reach the maximal current amplitude. Bottom panel, fipronil inhibition curves for the same receptors. The data are the means ± S.E. of n = 8–12 oocytes.
