Table 1.
Summary of the 50 Studies Included in Pooled Data for Presenting Features of Pyogenic Spondylodiscitis.
| Demographics | Presentation | Lesion Location | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| First Author, Year | Paper Type | Patients (n) | Men (n) | Mean Age (Years) | Time to Diagnosis (Days) | Back Pain | Neurological Findings | Cervical | Thoracic | Lumbar |
| Aagaard, 2013 | Retrospective review | 100 | 37 | 60 | 32 | 25 | 26 | 65 | ||
| Asamoto, 2005 | Retrospective review | 21 | 13 | 66 | 19 | 12 | 5 | 7 | 11 | |
| Ascione 2017 | Retrospective review | 30 | 13 | 64 | 28 | 30 | 5 | 0 | 2 | 20 |
| Bernard, 2015 | Randomized controlled trial | 351 | 242 | 61 | 337 | 57 | 52 | 96 | 246 | |
| Bettini, 2009 | Retrospective review | 56 | 21 | 48 | 34 | 56 | 18 | 3 | 8 | 48 |
| Butler, 2006 | Retrospective review | 48 | 24 | 59 | 47 | 14 | 4 | 11 | 30 | |
| Bydone, 2014 | Retrospective review | 118 | 57 | 67 | 61 | 35 | 40 | 43 | ||
| Cebrian, 2012 | Retrospective review | 108 | 49 | 68 | 97 | 27 | 4 | 38 | 66 | |
| Chung, 2011 | Retrospective review | 20 | 13 | 60 | 20 | 14 | 0 | 8 | 12 | |
| Citak, 2014 | Retrospective review | 183 | 99 | 63 | 80 | 14 | 66 | 97 | ||
| D’Agostino, 2010 | Prospective series | 81 | 51 | 58 | 55.4 | 79 | 12 | 10 | 59 | 12 |
| D’Aliberti, 2012 | Retrospective review | 40 | 29 | 56 | 39 | 16 | 13 | 18 | 9 | |
| Dennis, 2017 | Retrospective | 84 | 49 | 62 | 68 | 19 | 29 | 79 | 156 | |
| Eysel, 1997 | Retrospective review | 55 | 28 | 52 | ||||||
| Ha, 2007 | Retrospective review | 24 | 14 | 23 | 7 | 0 | 0 | 24 | ||
| Hadjipavlou, 2000 | Retrospective review | 101 | 76 | 46 | 40 | 10 | 33 | 55 | ||
| Heyde, 2006 | Retrospective review | 20 | 11 | 60 | 84 | 9 | ||||
| Homagk, 2016 | Retrospective review | 270 | 153 | 64 | 101 | 30 | 103 | 149 | ||
| Hopf, 1998 | Retrospective review | 72 | 39 | 52 | 0 | 40 | 49 | |||
| Karadimas, 2008 | Retrospective review | 163 | 101 | 56 | 13 | 72 | 88 | |||
| Kaya, 2014 | Retrospective review | 107 | 64 | 53 | 97 | 18 | 7 | 14 | 90 | |
| Kehrer, 2015 | Retrospective review | 298 | 182 | 66 | 33 | 38 | 95 | 203 | ||
| Klockner, 2003 | Retrospective review | 71 | 38 | 54 | 18 | 0 | 33 | 39 | ||
| Krodel, 1991 | Retrospective review | 24 | 50 | |||||||
| Legrand, 2001 | Retrospective review | 110 | 67 | 61 | 40 | 18 | 3 | 23 | 69 | |
| Lemaignen, 2017 | Retrospective review | 394 | 267 | 63 | 40 | 369 | 130 | 71 | 137 | 281 |
| Lin CP, 2012 | Retrospective review | 48 | 19 | 67 | 144 | 48 | 28 | 0 | 16 | 38 |
| Lin TY, 2014 | Retrospective review | 45 | 25 | 62 | 0 | 9 | 36 | |||
| Lin Y, 2015 | Retrospective review | 22 | 13 | 55 | 22 | 8 | 0 | 0 | 22 | |
| Lu, 2015 | Retrospective review | 28 | 13 | 60 | 6 | 0 | 2 | 28 | ||
| Mann, 2004 | Prospective series | 24 | 14 | 63 | 24 | 13 | 4 | 10 | 10 | |
| Nasto, 2014 | Retrospective review | 27 | 18 | 60 | 33 | 0 | 5 | 22 | ||
| Noh, 2017 | Retrospective review | 31 | 27 | 68 | 18 | 3 | 8 | 20 | ||
| Pee, 2008 | Retrospective review | 60 | 36 | 59 | 58 | 16 | 0 | 0 | 60 | |
| Rath, 1996 | Retrospective review | 43 | 24 | 60 | 46 | 35 | 0 | 19 | 24 | |
| Shinkel, 2003 | Retrospective review | 32 | 18 | 61 | 32 | 17 | 21 | 19 | 35 | |
| Schomacher, 2014 | Retrospective review | 37 | 24 | 62 | 37 | 6 | 6 | 25 | ||
| Shetty, 2016 | Retrospective review | 27 | 19 | 48 | 6 | |||||
| Shiban, 2014 | Retrospective review | 113 | 78 | 104 | 40 | |||||
| Shousha, 2012 | Retrospective review | 30 | 19 | 65 | 24 | 12 | 30 | 0 | 0 | |
| Sobottke, 2009 | Retrospective review | 20 | 14 | 43 | 23 | 3 | 2 | 6 | 12 | |
| Srinivasan, 2014 | Retrospective review | 48 | 29 | 56 | ||||||
| Suess, 2007 | Retrospective review | 24 | 15 | 65 | 9 | 24 | 7 | 3 | 14 | 7 |
| Tsai, 2017 | Retrospective review | 90 | 61 | 61 | ||||||
| Valancius, 2013 | Retrospective review | 196 | 106 | 52.5 | 177 | 47 | 9 | 42 | 125 | |
| Vcelak, 2014 | Retrospective review | 31 | 20 | 61 | 9 | 6 | 25 | |||
| Viale, 2009 | Prospective series | 48 | 36 | 60 | 9 | 6 | 9 | 29 | ||
| Wirtz, 2000 | Retrospective review | 59 | 29 | 61 | 90 | 46 | ||||
| Yaldz, 2015 | Retrospective review | 39 | 19 | 47 | 105 | 37 | 18 | 0 | 15 | 24 |
| Ziu, 2014 | Retrospective review | 102 | 87 | 45 | 102 | 26 | 9 | 24 | 59 | |