Table 4. PK of Compound 13 in CD-1 Mice^a.

dose	parameter	value
3 mg/kg IV	CL	46 mL/min/kg
	t1/2	0.96 h
	VSS	0.53 L/kg
100 mg/kg PO	Cmax	0.59 μg/mL
	Tmax	1.00 h
	AUCinf	0.88 h·μg/mL
	F	2.4%

^aCD-1 mice (n = 3/time-point) were dosed IV with 3 mg/kg or PO with 100 mg/kg compound 13 in 10% captisol and 50 mM sodium citrate, pH 5. Plasma was collected at 1, 5 (IV only), 15, and 30 min and 1, 2, 4, 8, 12, and 24 h, and PK parameters were calculated on the mean concentration data using noncompartmental analysis.