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| compound | Hep G2 toxicity IC50 (μM) ± SEM | therapeutic indexa |
|---|---|---|
| 4e | 13.0 ± 1.7 | 130 |
| 5a | 28.4 ± 8.3 | 171 |
| 11a | 19.3 ± 3.3 | 219 |
| 11c | 11.0 ± 0.7 | 333 |
| 11i | 21.2 ± 0.8 | 79 |
| rotenone | 1.52 ± 0.24 | |
| tamoxifen | 12.0 ± 0.5 |
Therapeutic index is determine by comparing the HepG2 IC50 values with the corresponding 3D7 IC50 values.
