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. 2018 Oct 31;18(12):7494–7501. doi: 10.1021/acs.nanolett.8b02916

Figure 4.

Figure 4

Probing hydrophobicity changes between non-ThT active and ThT active αS species (a) Hydrophobicity landscapes of non-ThT active and ThT active species from all time points for the 70 μM αS aggregation. (Lookup table: population density.) (b) Cartoon showing αS protein aggregation; each αS species in (A), (B), and (C) corresponds to the αS species indicated by the area in a white circle area in (a). (A) Non-ThT active small oligomers, (B) ThT active, β-sheet rich larger oligomers, and (C) ThT active, β-sheet rich fibrils.