Table 1.
Characteristics of the study population
| Variables | All patients (N = 158) | Unfavorable outcome group (N = 73) | Favorable outcome group (N = 85) | p value |
|---|---|---|---|---|
| Age (years) | 62.9 ± 15.9 | 69.6 ± 15.1 | 57.1 ± 14.4 | < 0.01 |
| Sex (male) | 52 (32.9) | 23 (31.5) | 29 (34.1) | 0.74 |
| H&K grade | < 0.01 | |||
| I | 13 (8.2) | 3 (4.1) | 10 (11.8) | |
| II | 60 (38.0) | 14 (19.2) | 46 (54.1) | |
| III | 41 (25.9) | 22 (30.1) | 19 (22.4) | |
| IV | 29 (18.4) | 23 (31.5) | 6 (7.1) | |
| V | 15 (9.5) | 11 (15.1) | 4 (4.7) | |
| Treatment modality | 0.27 | |||
| Coil | 117 (74.1) | 58 (79.5) | 59 (69.4) | |
| Clip | 39 (24.7) | 14 (19.2) | 25 (29.4) | |
| Number of arterial blood gas analyses on days 1–14 | 43 [31–55] | 53 [39–56] | 40 [28–48] | < 0.01 |
| Median PaCO2 on days 1–14 (mmHg) | 39.0 [37.2–40.9] | 38.4 [36.9–40.5] | 39.4 [37.4–40.9] | 0.11 |
| SD of PaCO2 on days 1–14 | 3.63 [2.75–4.60] | 4.05 [3.58–5.20] | 2.97 [2.45–3.95] | < 0.01 |
| Proportion of PaCO2 ≤ 30 among all blood gas analyses on days 1–14 (%) | 0 [0–2] | 2 [0–5] | 0 [0–0] | < 0.01 |
| Proportion of PaCO2 < 35 among all blood gas analyses on days 1–14 (%) | 14 [3–26] | 21 [9–35] | 9 [2–22] | < 0.01 |
| Proportion of PaCO2 > 45 among all blood gas analyses on days 1–14 (%) | 4 [0–16] | 7 [2–18] | 2 [0–12] | < 0.05 |
| Maximum PaCO2 level on days 1–14 (mmHg) | 47.4 [43.7–51.0] | 49.4 [45.6–51.9] | 45.8 [42.9–49.8] | < 0.01 |
| Minimum PaCO2 level on days 1–14 (mmHg) | 31.0 [28.7–33.8] | 29.4 [26.2–32.7] | 31.7 [30.2–34.5] | < 0.01 |
| Use of mechanical ventilation | 156 (98.7) | 73 (100) | 83 (97.6) | 0.50 |
| Modified Rankin scale score | < 0.01 | |||
| 0 | 29 (18.4) | 0 (0.0) | 29 (34.1) | |
| 1 | 27 (17.1) | 0 (0.0) | 27 (31.8) | |
| 2 | 29 (18.4) | 0 (0.0) | 29 (34.1) | |
| 3 | 24 (15.2) | 24 (32.9) | 0 (0.0) | |
| 4 | 27 (17.1) | 27 (37.0) | 0 (0.0) | |
| 5 | 12 (7.6) | 12 (16.4) | 0 (0.0) | |
| 6 | 10 (6.3) | 10 (13.7) | 0 (0.0) | |
| DCI | 23 (14.6) | 16 (21.9) | 7 (8.2) | < 0.05 |
| Mechanical ventilation duration | 2 [1–9] | 9 [2–16] | 1 [1–2] | < 0.01 |
| ICU stay duration | 15 [12–19] | 17 [13–21] | 14 [12–16] | < 0.01 |
| Hospital stay duration | 28 [22–51] | 41 [26–74] | 24 [21–30] | < 0.01 |
| Hospital mortality | 10 (6.3) | 10 (13.7) | 0 (0.0) | < 0.01 |
Data are presented as mean ± standard deviation (SD), number (percentage), or median [interquartile range]
H&K Hunt and Kosnik, DCI Delayed cerebral ischemia, ICU Intensive care unit