Table 2.
Analysis of presenting blood counts for MPNs according to sex, race, JAK2 V617F mutation and MPN sub-types
| Groups | HB, g/dL | HCT, % | PLT, × 109/L | WBC, × 109/L | ||||
|---|---|---|---|---|---|---|---|---|
| Mean (sd) | p-value | Mean (sd) | p-value | Mean (sd) | p-value | Mean (sd) | p-value | |
| A. Ethnic groups | ||||||||
| Malay | 14.58 (3.99) | 0.350 | 44.96 (13.13) | 0.338 | 716.61 (415.30) | < 0.001 | 17.75 (13.98) | 0.326 |
| Chinese | 14.41 (3.59) | 44.04 (11.57) | 755.20 (444.96) | 16.62 (18.09) | ||||
| Indian | 15.43 (4.06) | 46.45 (12.50) | 503.92 (305.49) | 14.01 (10.64) | ||||
| Native—Sabah | 14.53 (4.73) | 47.57 (14.91) | 807.39 (765.28) | 19.43 (13.39) | ||||
| Native—Sarawak | 15.17 (2.62) | 46.05 (6.67) | 946.26 (515.50) | 16.59 (10.18) | ||||
| B. JAK2 V617F mutation | ||||||||
| Negative | 13.63 (3.43) | < 0.001 | 41.14 (10.36) | < 0.001 | 732.84 (498.21) | 0.923 | 12.92 (12.72) | < 0.001 |
| Positive | 15.17 (3.80) | 46.90 (12.30) | 729.58 (404.97) | 17.76 (14.13) | ||||
| C. Sub-types | ||||||||
| ET | 13.08 (2.10) | < 0.001 | 39.75 (7.24) | < 0.001 | 1032.20 (424.77) | < 0.001 | 13.36 (7.74) | < 0.001 |
| PV | 17.86 (3.01) | 54.73 (10.32) | 539.60 (299.68) | 16.61 (9.70) | ||||
| PMF | 9.86 (2.60) | 29.88 (8.42) | 350.79 (320.11) | 22.37 (31.60) | ||||
| HES | 12.29 (2.71) | 36.41 (8.56) | 296.63 (241.85) | 23.75 (15.24) | ||||
| MPN-U | 12.91 (3.66) | 40.57 (10.95) | 741.46 (446.61) | 27.68 (23.46) | ||||