Table 3.
Comparisons the levels of 8-OH-dG, 8-iso-PGF2α and hsCRP before and after 8-week treatment between two groups
| Variable | Liraglutide group | Metformin group | ||||
|---|---|---|---|---|---|---|
| Pre-treatment | Post-treatment | P-value | Pre-treatment | Post-treatment | P-value | |
| 8-OH-dG (ng/mL) | 35.95 (29.30, 50.70) |
18.74 (4.84, 24.20) |
0.002 | 16.77 (9.71, 32.60) |
7.86 (2.87, 23.31) |
0.027 |
| 8-iso-PGF2α (ng/mL) | 1345 (885, 1920) |
288 (183, 472) |
0.001 | 1180 (1025, 1765) |
299 (228, 586) |
0.001 |
| hsCRP (mg/L) | 1.96 (1.11, 3.89) |
1.47 (0.53, 1.86) |
0.002 | 1.88 (1.06, 3.69) |
1.44 (0.67, 2.35) |
0.017 |
Data are expressed as median (interquartile rang)
8-OH-dG, 8-hydroxy-2′-deoxyguanosine; 8-iso-PGF2α, 8-isoprostane F2α; hsCRP, high sensitivity C-reactive protein