Table 1. Remaining Hydrolase Activity for hABHD12 and hABHD16A (% Control) at 10 μM Concentration.
compd | hABHD16A (% control) mean ± SD, n = 2–3 | hABHD12 (% control) mean ± SD, n = 2–3 |
---|---|---|
5 | 58.2 ± 18.1 | 102.6 ± 2.3 |
6 | 50.3 ± 4.6 | 91.5 ± 0.4 |
7 | 74.6 ± 7.5 | 87.8 ± 0.8 |
8 | 65.9 ± 2.8 | 96.3 ± 1.0 |
11 | 80.0 ± 5.6 | 96.9 ± 0.8 |
12 | 82.1 ± 4.3 | 98.7 ± 0.2 |
13 | 91.5 ± 2.8 | 98.4 ± 0.2 |
14 | 62.9 ± 3.4 | 77.8 ± 1.0 |
15 | 73.8 ± 4.7 | 89.8 ± 0.1 |
16 | 86.6 ± 0.8 | 100.9 ± 4.1 |
17 | 99.3 ± 2.4 | 96.6 ± 8.8 |
18 | 23.0 ± 16.3 | 100.1 ± 1.1 |
19 | 48.7 ± 0.5 | 73.8 ± 3.2 |
20 | 42.8 ± 4.1 | 94.3 ± 0.7 |
21 | 66.3 ± 5.9 | 98.7 ± 2.2 |
22 | 98.4 ± 0.8 | 101.9 ± 0.0 |
23 | 80.6 ± 1.8 | 99.6 ± 1.0 |
24 | 82.7 ± 4.2 | 92.8 ± 1.2 |
25 | 81.5 ± 4.9 | 91.1 ± 1.7 |
26 | 80.1 ± 1.6 | 91.1 ± 2.9 |