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. 2018 Nov 13;9(12):1269–1273. doi: 10.1021/acsmedchemlett.8b00442

Table 1. Remaining Hydrolase Activity for hABHD12 and hABHD16A (% Control) at 10 μM Concentration.

compd hABHD16A (% control) mean ± SD, n = 2–3 hABHD12 (% control) mean ± SD, n = 2–3
5 58.2 ± 18.1 102.6 ± 2.3
6 50.3 ± 4.6 91.5 ± 0.4
7 74.6 ± 7.5 87.8 ± 0.8
8 65.9 ± 2.8 96.3 ± 1.0
11 80.0 ± 5.6 96.9 ± 0.8
12 82.1 ± 4.3 98.7 ± 0.2
13 91.5 ± 2.8 98.4 ± 0.2
14 62.9 ± 3.4 77.8 ± 1.0
15 73.8 ± 4.7 89.8 ± 0.1
16 86.6 ± 0.8 100.9 ± 4.1
17 99.3 ± 2.4 96.6 ± 8.8
18 23.0 ± 16.3 100.1 ± 1.1
19 48.7 ± 0.5 73.8 ± 3.2
20 42.8 ± 4.1 94.3 ± 0.7
21 66.3 ± 5.9 98.7 ± 2.2
22 98.4 ± 0.8 101.9 ± 0.0
23 80.6 ± 1.8 99.6 ± 1.0
24 82.7 ± 4.2 92.8 ± 1.2
25 81.5 ± 4.9 91.1 ± 1.7
26 80.1 ± 1.6 91.1 ± 2.9