Table 1.
Particle size, PDI, zeta potential, EE, and DLC of NLC (mean±SD, n=3)
| Formulation | Particle size (nm) | PDI | Zeta potential (mV) | EE (%) | DL (%) |
|---|---|---|---|---|---|
| TPGS/LID-NLC | 167.6±4.3 | 0.156±0.026 | +21.2±2.3 | 85.9±3.1 | 11.5±0.9 |
| TPGS-NLC | 163.9±3.8 | 0.137±0.015 | +23.5±2.8 | – | – |
| LID-NLC | 148.8±2.9 | 0.121±0.012 | +34.7±3.6 | 87.1±2.6 | 18.2±1.1 |
Abbreviations: DLC, drug-loading capacity; EE, entrapment efficiency; LID, lidocaine; NLC, nanostructured lipid carriers; PDI, polydispersity index; TPGS, tocopheryl polyethylene glycol 1000 succinate.