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. 2018 Dec 12;11:9013–9025. doi: 10.2147/OTT.S183847

Figure 2.

Figure 2

miR-769 regulates CRC cell proliferation, apoptosis, migration, and invasion in vitro.

Notes: (A) miR-769 was markedly upregulated in HCT116 and SW480 cells after transfection with miR-769 mimics. *P<0.05. miR-NC. (B) MTT assay after the transfection with miR-769 mimics or miR-NC in HCT116 and SW480 cells. *P<0.05. miR-NC. (C) Flow cytometry analysis was used to determine the apoptosis rate of HCT116 and SW480 cells that were transfected with miR-769 mimics or miR-NC. *P<0.05. miR-NC. (D, E) Migration and invasion assays were used to determine the migratory and invasive capacities of HCT116 and SW480 cells transfected with miR-769 mimics or miR-NC, respectively. *P<0.05. miR-NC.

Abbreviations: CRC, colorectal cancer; miR-NC, negative control miRNA mimics.