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. 2018 Dec 12;11:9013–9025. doi: 10.2147/OTT.S183847

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© 2018 Wang et al. This work is published and licensed by Dove Medical Press Limited

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CDK1 is overexpressed in CRC tissue samples and negatively correlates with miR-769 expression.

Notes: (A) CDK1 mRNA level was detected in clinical CRC tissues by RT-qPCR analysis. *P<0.05. ANTs. (B, C) Western blot analysis was used to measure CDK1 protein level in several pairs of CRC tissues and ANTs. *P<0.05. ANTs. (D) The correlation between miR-769 and CDK1 mRNA expression in clinical CRC tissues was assessed by Spearman’s correlation analysis. r=-0.5336, P=0.0001.

Abbreviations: ANTs, adjacent normal tissues; CDK1, cyclin-dependent kinase 1; CRC, colorectal cancer; RT-qPCR, reverse transcription-quantitative PCR.