Figure 7.

miR-769 inhibits CRC cell growth in vivo.

Notes: (A) The representative images of the miR-769 mimics and miR-NC tumor xenografts. (B) The volume of tumor xenografts from the miR-769 mimics and miR-NC groups was determined after inoculation. *P<0.05 vs miR-NC. (C) Nude mice were sacrificed at 30 days after injection. The weights of tumor xenografts were weighted. *P<0.05 vs miR-NC. (D) RT-qPCR analysis was utilized to determine miR-769 expression in the tumor xenografts. *P<0.05 vs miR-NC. (E) Expression level of CDK1 protein in the tumor xenografts was detected through Western blot analysis.

Abbreviations: CDK1, cyclin-dependent kinase 1; CRC, colorectal cancer; miR-NC, negative control miRNA mimics.