Table 2.
Probable HeFH sample: demographic and clinical characteristics
| Demographic and clinical characteristics | Probable HeFH patients |
|---|---|
| Index LDL-C value >190 mg/dL n=4,137 (2.2%) | |
| Age in years, mean (SD) | 65.32 (11.57) |
| Age groups, % | |
| <18 | 0.0 |
| 18–44 | 3.9 |
| 45–54 | 14.6 |
| 55–64 | 26.9 |
| >65 | 54.7 |
| Gender, % | |
| Male | 33.9 |
| Female | 66.1 |
| Geographic region, % | |
| Northeast | 25.7 |
| South | 40.4 |
| Midwest | 21.3 |
| West | 12.6 |
| CCI score, % | |
| 0 | 99.2 |
| >0 | 0.8 |
| Mean (SD) | 0.01 (0.09) |
| Comorbidities, % | |
| Diabetes | 26.0 |
| Hypertension | 62.7 |
| Dyslipidemia | 72.0 |
| Coronary disease | 40.2 |
| Cerebrovascular disease | 18.2 |
| Peripheral vascular disease | 52.5 |
| Index LDL-C, mg/dL | |
| Mean (SD) | 215.97 (30.92) |
| Number of LDL-C tests, % | |
| 1 (index test) | 38.0 |
| 2 | 31.3 |
| 3 | 16.7 |
| 4 | 8.1 |
| >4 | 5.9 |
| Medications, % | |
| Antidiabetic | 16.3 |
| Antiarrhythmic | 0.3 |
| Antihypertensive | 56.2 |
| Index BMI | |
| Patients with BMI, % | 90.8 |
| Mean (SD) | 29.63 (6.49) |
Abbreviations: BMI, body mass index; CCI, Charlson Comorbidity Index; HeFH, heterozygous familial hypercholesterolemia; LDL-C, low-density lipoprotein cholesterol.