Table 2. Medications during the first 24 hours of post cardiac arrest care.
| Medications | All patients (N = 81) | NMB (n = 38) | Placebo (n = 43) | p Value |
|---|---|---|---|---|
| Vasopressors | ||||
| Dopamine, n (%) | 39 (48.1) | 19 (50.0) | 20 (46.5) | 0.754 |
| Dose of dopamine, mg | 769 (360–1,616) | 646 (235–2,332) | 883 (500–1,600) | 0.844 |
| Norepinephrine, n (%) | 62 (76.5) | 13 (81.6) | 31 (72.1) | 0.315 |
| Dose of norepinephrine, mg | 10.3 (0.7–30.0) | 9.4 (1.2–34.1) | 12.0 (0.6–27.0) | 0.899 |
| Vasopressin, n (%) | 11 (13.6) | 7 (18.4) | 4 (9.3) | 0.232 |
| Dose of vasopressin, IU | 40.0 (13.0–50.0) | 27.3 (1.0–50.0) | 49.4 (42.3–61.2) | 0.186 |
| Epinephrine, n (%) | 4 (4.9) | 2 (5.3) | 2 (4.7) | 1.000 |
| Sedatives and analgesics | ||||
| Midazolam, n (%) | 68 (84.0) | 31 (81.6) | 37 (86.0) | 0.585 |
| Dose of midazolam, mg | 89.0 (52.4–154.3) | 72.2 (52.8–180.0) | 90.0 (50.7–145.9) | 0.430 |
| Propofol, n (%) | 9 (11.1) | 5 (13.2) | 4 (9.3) | 0.728 |
| Dose of propofol, g | 2.4 (1.8–5.0) | 2.4 (1.7–6.2) | 2.3 (1.8–3.7) | 0.806 |
| Remifentanil, n (%) | 40 (49.4) | 17 (44.7) | 23 (53.5) | 0.432 |
| Dose of remifentanil, mg | 9.6 (7.0–12.0) | 9.6 (7.1–12.0) | 9.6 (4.6–12.0) | 0.619 |
| Morphine, n (%) | 2 (2.5) | 1 (2.6) | 1 (2.3) | 1.000 |
| Neuromuscular blockade | ||||
| Continuous rocuronium, mg | 548 (318–720) | 548 (318–720) | NA | |
| Bolus neuromuscular blockade | 16 (19.8) | 3 (7.9) | 13 (30.2) | 0.012 |
| Bolus rocuronium, n (%) | 5 (6.2) | 0 (0.0) | 5 (11.6) | 0.057 |
| Bolus vecuronium, n (%) | 10 (12.3) | 2 (5.3) | 8 (18.6) | 0.069 |
| Bolus cis-atracurium, n (%) | 2 (2.5) | 1 (2.6) | 2 (2.3) | 1.000 |
NMB, neuromuscular blockade