Table 3. Primary outcome and clinical outcomes.
Outcomes | All patients (N = 81) | NMB (n = 38) | Placebo (n = 43) | p Value |
---|---|---|---|---|
Primary outcome | ||||
Serum lactate at 24 hours | 3.0 (1.7–4.3) | 2.8 (1.2–4.0) | 3.6 (1.8–5.2) | 0.238 |
Clinical outcome | ||||
In-hospital mortality | 40 (49.4) | 17 (44.7) | 23 (53.5) | 0.432 |
Poor neurologic outcome (CPC 3 to 5) | 61 (75.3) | 29 (76.3) | 32 (74.4) | 0.843 |
Poor neurologic outcome (mRS 4 to 6) | 62 (76.5) | 29 (76.3) | 33 (76.7) | 0.964 |
Length of stay | ||||
ICU stay | 7.4 (2.8–13.7) | 8.0 (2.4–15.2) | 6.4 (2.9–11.6) | 0.481 |
Hospital stay | 9.0 (3.0–18.0) | 11.5 (2.0–21.3) | 8.0 (3.0–18.0) | 0.673 |
Discharge to home | ||||
All patients | 15 (18.5) | 7 (18.4) | 8 (18.6) | 0.983 |
Hospital survivors | 15/41 (36.6) | 7/21 (33.3) | 8/20 (40.0) | 0.658 |
NMB, neuromuscular blockade; CPC, cerebral performance category; mRS, modified Rankin score; ICU, intensive care unit