Skip to main content
. 2018 Dec 17;13(12):e0208905. doi: 10.1371/journal.pone.0208905

Table 3. Subgroup analysis of adiponectin associations with diabetic nephropathy.

    Test of association Test of heterogeneity
  n SMD 95% CI Pa Pb I2 (%) AM
T1DM
    CN v MI 4 1.74 0.78, 2.69 0.0004 10−5 97 R
    CN v MA 4 1.39 0.88, 1.89 10−5 10−5 93 R
    NO v MI 5 1.10 0.13, 2.07 0.03 10−5 99 R
    NO v MA 5 2.26 0.97, 3.56 0.0006 10−5 99 R
    MI v MA 6 0.75 0.22,1.29 0.006 10−5 95 R
T2DM
    CN v MI 2 -1.44 -1.85, -1.03 10−5 0.48 0 F
    CN v MA 3 -0.25 -2.28, 1.78 0.81 10−5 97 R
    NO v MI 5 0.46 0.25, 0.68 10−5 0.43 0 F
    NO v MA 5 1.40 0.93, 1.87 10−5 0.03 62 R
    MI v MA 6 0.64 -0.29, 1.57 0.18 10−5 92 R

T1DM: Type 1 diabetes mellitus; T2DM: Type 2 diabetes mellitus; CN: control; NO: normoalbuminuria; MI: microalbuminuria; MA: macroalbuminuria; v: versus; n: number of studies; SMD: standardized mean difference; CI: confidence interval; Pa: P-value for association; Pb: P-value for heterogeneity; AM: analysis model; F: fixed-effects, R: random-effects