Table 5. Estimated regression coefficients for the relationship between urinary phthalate metabolites and delayed responses of peak expiratory flow rate (PEFR).
| Phthalate metabolites | Lagged day | Estimate (95% confidence interval) | |
|---|---|---|---|
| Basic modela | Model with outdoor environmentb | ||
| MEHHP | LAG0 | -7.18 (-15.74, 1.39) | -8.40 (-17.39, 0.60) |
| LAG1 | -9.18 (-18.17, -0.18)* | -12.17 (-21.74, -2.59)* | |
| LAG2 | -4.30 (-11.87, 3.28) | -5.00 (-12.70, 2.69) | |
| MEOHP | LAG0 | -7.28 (-16.25, 1.69) | -7.50 (-16.89, 1.90) |
| LAG1 | -9.42 (-19.39, 0.54) | -10.80 (-21.32, -0.29)* | |
| LAG2 | -3.86 (-11.99, 4.26) | -2.74 (-11.04, 5.56) | |
| MnBP | LAG0 | -5.28 (-13.31, 2.75) | -7.42 (-15.87, 1.04) |
| LAG1 | -10.50 (-18.92, -2.07)* | -13.65 (-22.24, -5.07)* | |
| LAG2 | -3.67 (-10.48, 3.13) | -5.47 (-12.23, 1.30) | |
All results were quantified according to natural log-transformed concentrations of urinary phthalate metabolites
*statistically significant
aresults from basic LME model controlling for age, sex, body mass index, urinary cotinine, and the use of controller medication
bresults from LME model with outdoor environments as additional confounders; all effects were quantified per natural log-transformed concentrations of urinary phthalate metabolites; MEHHP: mono-(2-ethyl-5-hydroxyhexyl) phthalate; MEOHP: mono-(2-ethyl- 5-oxohexyl) phthalate; and MnBP: mono-n-butyl phthalate.