Table 3.

Serum values of growth differentiation factor-15 (GDF-15) AFP, and ferritin in controls as and studied groups.

Parameter	Statistics	Normal control (NC) (N = 20)	Chronic hepatitis C G (I) (N = 20)	Liver cirrhosis G (II) (N = 23)	Hepatocellular carcinoma G (III) (N = 17)
GFD15 (ng/ml)	Range	0.30–1.05	0.45 – 3.50	3.4–6.70	4.5–8.79
	Mean ± S.E.	0.70 ± 0.052	1.41 ± 0.21	5.20 ± 0.21	6.49 ± 0.27
	P-value <		<0.01	<0.001	<0.001
AFP (ng/ml)	Range	2.1–5.7	3.5–9.3	13.8–36.4	218–351
	Mean ± S.E.	3.88 ± 0.25	6.63 ± 0.29	28.04 ± 1.85	255 ± 7.53
	P-value <		<0.001	<0.001	<0.001
Ferritin (ng/ml)	Range	30–203	75–273	124–382	243–764
	Mean ± S.E.	95 ± 11.28	162.5 ± 14.13	252 ± 16.06	504 ± 11.96
	P-value <		<0.001	<0.001	<0.001

P < 0.05 as statistically significant.