Table 1.
Demographic and biochemical variables of the studied population.
| T2DM (N = 105) | T2DM with CAD (N = 100) | CAD (N = 100) | Controls (N = 100) | P value |
|
| mean ± SEM | mean ± SEM | mean ± SEM | mean ± SEM | ||
| Age (year) | 47.89 ± 1.14 | 49.53 ± 0.87 | 48.94 ± 0.88 | 48 ± 0.95 | 0.974 |
| Height (cm) | 163.47 ± 0.91 | 166.93 ± 1.01 | 169.83 ± 0.75 | 165.6 ± 1.07 | <0.001** |
| Weight (Kg) | 82.17 ± 1.13 | 90.51 ± 1.20 | 95.08 ± 1.11 | 74.12 ± 1.33 | <0.001** |
| Waist (cm) | 94.22 ± 1.89 | 109.52 ± 1.06 | 102.48 ± 1.20 | 88.34 ± 1.22 | <0.001** |
| BMI (Kg/m2) | 30.9 ± 0.46 | 32.58 ± 0.41 | 33.15 ± 0.48 | 27.26 ± 0.59 | <0.001** |
| SBP (mm Hg) | 127.95 ± 1.34 | 143.9 ± 1.66 | 148.45 ± 1.63 | 120.6 ± 1.24 | <0.001** |
| DBP (mm Hg) | 84.14 ± 1.0 | 89.15 ± 1.25 | 92.4 ± 1.24 | 80 ± 1.01 | <0.001** |
| FBG (mg/dl) | 175.56 ± 8.65 | 207.88 ± 5.82 | 93.13 ± 2.13 | 91.09 ± 2.01 | <0.001** |
| 2HPP (mg/dl) | 207.67 ± 9.69 | 245.17 ± 8.34 | 100.6 ± 1.96 | 97.82 ± 2.21 | <0.001** |
| HbA1c % | 8.04 ± 0.22 | 8.34 ± 0.15 | 5.58 ± 0.08 | 5.15 ± 0.07 | <0.001** |
| CHOL (mg/dl) | 206.73 ± 4.72 | 207.9 ± 5.20 | 209.55 ± 6.10 | 163.78 ± 3.35 | <0.001** |
| TG (mg/dl) | 172.91 ± 10.19 | 192.26 ± 7.49 | 171.27 ± 6.38 | 102.51 ± 3.41 | <0.001** |
| HDL (mg/dl) | 50.69 ± 1.47 | 34.5 ± 0.88 | 33.18 ± 0.93 | 49.16 ± 0.99 | <0.001** |
| LDL (mg/dl) | 122.11 ± 3.79 | 133.45 ± 5.01 | 141.2 ± 5.82 | 92.96 ± 3.54 | <0.001** |
| CRP (mg/L) | 129.02 ± 7.87 | 117.29 ± 5.92 | 120.38 ± 4.64 | 70.14 ± 3.81 | <0.001** |
| INS (mIU/L) | 15.58 ± 2.37 | 11.33 ± 2.44 | 13.99 ± 1.65 | 6.86 ± 0.89 | 0.009 |
| PON1 (mIU/mL) | 31.05 ± 1.04 | 25.82 ± 1.31 | 25.87 ± 0.76 | 82.94 ± 3.36 | <0.001** |
T2DM: Type 2 diabetes mellitus, T2DM with CAD: Type 2 diabetes mellitus with coronary artery diseases, CAD: coronary artery diseases, BMI: body mass index, SBP: systolic blood pressure, DBP: diastolic blood pressure, FBG: fasting blood glucose, 2HPP: 2 hours post prandial, HbA1c: heamoglobin A1c (glycated heamoglobin), CHOL: cholesterol, TG: triglyceride, HDL: high density lipoprotein, LDL: low density lipoprotein, CRP: c-reactive protein, INS: insulin and PON1: paraoxenase 1.
*The mean difference is significant at the 0.05 level (2-tailed).
**
The mean difference is highly significant at the 0.01 level (2-tailed).