Table 4.
Relation of PPAR-γ Pro12Ala gene polymorphisms and characteristics of subjects among T2DM group.
| T2DM (N = 105) | |||
|---|---|---|---|
| G (6.2%) Mean ± SEM | C (93.8%) Mean ± SEM | P value | |
| Height (cm) | 164.2 ± 0.93 | 163.4 ± 0.91 | 0.756 |
| Weight (kg) | 87.1 ± 1.53 | 81.9 ± 1.1 | 0.248 |
| Waist (cm) | 100.2 ± 1.61 | 93.8 ± 1.9 | 0.292 |
| BMI (kg/m2) | 32.2 ± 0.45 | 30.8 ± 0.46 | 0.243 |
| SBP (mm Hg) | 133.1 ± 1.25 | 127.6 ± 1.33 | 0.152 |
| DBP (mm Hg) | 86.5 ± 0.66 | 84.0 ± 1.01 | 0.371 |
| FBG (mg/dL) | 184.4 ± 8.08 | 175.0 ± 8.68 | 0.704 |
| 2HPP (mg/dL) | 252.2 ± 1.01 | 204.7 ± 9.6 | 0.087 |
| HbA1c % | 8.7 ± 0.27 | 8.0 ± 0.21 | 0.229 |
| CHOL (mg/dL) | 214.5 ± 4.34 | 206.2 ± 4.74 | 0.543 |
| TG (mg/dL) | 169.6 ± 8.58 | 173.1 ± 10.3 | 0.905 |
| HDL (mg/dL) | 50.2 ± 1.34 | 50.7 ± 1.48 | 0.893 |
| LDL (mg/dL) | 130.4 ± 3.37 | 121.6 ± 3.81 | 0.415 |
| CRP (mg/L) | 1.71 ± 0.11 | 1.26 ± 0.75 | 0.191 |
| INS (mIU/L) | 19.9 ± 2.09 | 15.3 ± 2.39 | 0.494 |
| PON1 (mIU/ml) | 29.5 ± 1.31 | 31.2 ± 1.02 | 0.57 |
T2DM: Type 2 diabetes mellitus, BMI: body mass index, SBP: systolic blood pressure, DBP: diastolic blood pressure, FBG: fasting blood glucose, 2HPP: 2 hours post prandial, HbA1c: heamoglobin A1c (glycated heamoglobin), CHOL: cholesterol, TG: triglyceride, HDL: high density lipoprotein, LDL: low density lipoprotein, CRP: c-reactive protein, INS: insulin and PON1: paraoxenase 1.
*The mean difference is significant at the 0.05 level (2-tailed).
**The mean difference is highly significant at the 0.01 level (2-tailed).