Table 6.
Relation of PPAR-γ Pro12Ala gene polymorphisms and characteristics of subjects among CAD group.
| CAD (N = 100) | |||
|---|---|---|---|
| G (9.5%) Mean ± SEM | C (90.5%) Mean ± SEM | P value | |
| Height (cm) | 169.9 ± 0.75 | 169.8 ± 0.75 | 0.929 |
| Weight (kg) | 109.4 ± 1.4 | 93.5 ± 0.94 | <0.001* |
| Waist (cm) | 114.1 ± 1.0 | 101 ± 1.15 | <0.001* |
| BMI (kg/m2) | 38.0 ± 0.53 | 32.6 ± 0.44 | <0.001* |
| SBP (mm Hg) | 160.3 ± 0.77 | 147 ± 1.56 | <0.001* |
| DBP (mm Hg) | 102 ± 1.31 | 91.4 ± 1.19 | <0.001* |
| FBG (mg/dL) | 98.4 ± 1.79 | 92.6 ± 2.15 | 0.259 |
| 2 HPP (mg/dL) | 105.6 ± 1.7 | 100 ± 1.97 | 0.235 |
| HbA1c % | 5.9 ± 0.044 | 5.5 ± 0.078 | 0.019 |
| CHOL (mg/dL) | 239 ± 6.44 | 206.4 ± 6.0 | 0.027 |
| TG (mg/dL) | 190.1 ± 6.3 | 169.3 ± 6.4 | 0.176 |
| HDL (mg/dL) | 30.4 ± 0.45 | 33.4 ± 0.96 | 0.02 |
| LDL (mg/dL) | 170.3 ± 5.8 | 138.1 ± 5.7 | 0.021 |
| CRP (mg/L) | 1.14 ± 0.048 | 1.21 ± 0.046 | 0.556 |
| INS (mIU/L) | 19.6 ± 1.72 | 13.4 ± 1.63 | 0.117 |
| PON1 (mIU/ml) | 25.5 ± 0.59 | 25.9 ± 0.78 | 0.839 |
CAD: coronary artery diseases, BMI: body mass index, SBP: systolic blood pressure, DBP: diastolic blood pressure, FBG: fasting blood glucose, 2HPP: 2 hours post prandial, HbA1c: heamoglobin A1c (glycated heamoglobin), CHOL: cholesterol, TG: triglyceride, HDL: high density lipoprotein, LDL: low density lipoprotein, CRP: c-reactive protein, INS: insulin and PON1: paraoxenase 1.
**The mean difference is highly significant at the 0.01 level (2-tailed).
*
The mean difference is significant at the 0.05 level (2-tailed).