Table 5. Cross-reactivity profile of anti-CHIKV mAbs against flavivirus-infected cells.
Immunization strategy |
mAb | Cross reactivity test | |
---|---|---|---|
DENV 1–4 | ZIKV (SV0010/15) |
||
B | 3D11 | - | - |
11E11 | - | - | |
13H11 | - | - | |
15B2 | - | - | |
19B8 | - | - | |
RC5-3 | - | - | |
C | 24B3 | - | - |
26A2 | - | - | |
32A3a | - | - | |
37C7 | - | - | |
41G5 | - | - | |
Control mAb | 4G2a | + | + |
Alexa Fluor 488 signals of each photo were quantified by NIS-Elements software (Nikon Corporation, Tokyo, Japan). Note; + (positive; mean fluorescence intensity/pixel ≥ 15),—(negative; < 5)
a Positive control for Flaviviruses (DENV and ZIKV)